Oral clonidine reduces postoperative PCA morphine requirements
نویسندگان
چکیده
منابع مشابه
Oral clonidine premedication reduces postoperative pain in children.
Clonidine is an effective preanesthetic medication in children, providing a preoperative sedative effect. The analgesic properties of the drug have been well documented in adults. The current study was designed to investigate the effect of oral clonidine given preoperatively on postoperative pain in children undergoing minor surgery. In a prospective, randomized, controlled clinical trial, 90 c...
متن کاملOral Morphine Consumption Reduces Lens Development in Rat Embryos
Introduction: Consumption of morphine, during pregnancy, in addition to inducing defects in the mother’s nervous system function, caused defects or delays in the formation and evolution of embryonic visual system. In the present study, changes in lens development were assessed in embryos exposed to morphine in utero. Methods: Female Wistar rats (250-300 g) were mated with male rats and pregnanc...
متن کاملOral clonidine premedication reduces vomiting in children after strabismus surgery.
This is a prospective randomized double-blind trial conducted to determine whether preoperative orally administered clonidine causes or potentiates postoperative vomiting in 140 children (3-12 yr) undergoing strabismus surgery. They were all inpatients and classified randomly into four groups (n = 35 each); placebo (control), diazepam 0.4 mg.kg-1, clonidine 2 micrograms.kg-1, and clonidine 4 mi...
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BACKGROUND Multimodal analgesia is advocated for perioperative pain management to reduce opioid use and its associated adverse effects. Serotonin and norepinephrine are involved in the modulation of endogenous analgesic mechanisms via descending inhibitory pain pathways in the brain and spinal cord. An increase in serotonin and norepinephrine may increase inhibition of nociceptive input and imp...
متن کاملoral morphine consumption reduces lens development in rat embryos
introduction: consumption of morphine, during pregnancy, in addition to inducing defects in the mother’s nervous system function, caused defects or delays in the formation and evolution of embryonic visual system. in the present study, changes in lens development were assessed in embryos exposed to morphine in utero. methods: female wistar rats (250-300 g) were mated with male rats and pregnanc...
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ژورنال
عنوان ژورنال: Canadian Journal of Anaesthesia
سال: 1996
ISSN: 0832-610X,1496-8975
DOI: 10.1007/bf03011802